HPLC analysis of metabolically produced formaldehyde

J. Lengyel, H. Kalász, T. Szarvas, Cs Peltz, A. Szarkáné-Bolehovszky

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Radiolabelled (-)-deprenyl is orally administered to rats, and urinary elimination of radiolabelled formaldehyde is detected. The separation is performed using high-performance liquid chromatography on octadecyl-silica stationary phase. Both the radioactivity and the UV absorbance of the dinitrophenylhydrazine formaldehyde peak are determined. Formaldehyde generation takes place by N-demethylation. Low levels of formaldehyde may have a beneficial role in counterbalancing the oxidative stress of the everyday person's life.

Original languageEnglish
Pages (from-to)177-181
Number of pages5
JournalJournal of chromatographic science
Volume41
Issue number4
DOIs
Publication statusPublished - Apr 2003

ASJC Scopus subject areas

  • Analytical Chemistry

Fingerprint Dive into the research topics of 'HPLC analysis of metabolically produced formaldehyde'. Together they form a unique fingerprint.

  • Cite this

    Lengyel, J., Kalász, H., Szarvas, T., Peltz, C., & Szarkáné-Bolehovszky, A. (2003). HPLC analysis of metabolically produced formaldehyde. Journal of chromatographic science, 41(4), 177-181. https://doi.org/10.1093/chromsci/41.4.177