How do American stroke risk functions perform in a Western European population?

Z. Vokó, Monika Hollander, Peter J. Koudstaal, Albert Hofman, Monique M B Breteler

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Objectives: We evaluated the predictive performance of the stroke risk functions from the Framingham and the Cardiovascular Health Study in a population-based study in The Netherlands. Methods: We assessed how well the functions could estimate the number of strokes in the Rotterdam Study, and how well they could discriminate between high- and low-risk persons. Results: Both functions predicted the number of stroke cases reasonably well, except in persons with a predicted 5-year risk higher than 5%, where they overestimated the risk. The area under the receiver operator characteristic curve was 0.75 (95% confidence interval, 0.71-0.78) for both functions. Conclusions: Stroke risk functions developed in US populations predict the number of strokes reasonably well in elderly Western European persons at low or modest risk for stroke. The functions can be a useful tool to discriminate between persons at high or low risk for stroke.

Original languageEnglish
Pages (from-to)247-253
Number of pages7
JournalNeuroepidemiology
Volume23
Issue number5
DOIs
Publication statusPublished - 2004

Fingerprint

Stroke
Population
Netherlands
Confidence Intervals
Health

Keywords

  • Cerebrovascular disorders
  • Cohort studies
  • Risk assessment
  • Risk factors
  • Stroke

ASJC Scopus subject areas

  • Epidemiology
  • Clinical Neurology

Cite this

Vokó, Z., Hollander, M., Koudstaal, P. J., Hofman, A., & Breteler, M. M. B. (2004). How do American stroke risk functions perform in a Western European population? Neuroepidemiology, 23(5), 247-253. https://doi.org/10.1159/000079951

How do American stroke risk functions perform in a Western European population? / Vokó, Z.; Hollander, Monika; Koudstaal, Peter J.; Hofman, Albert; Breteler, Monique M B.

In: Neuroepidemiology, Vol. 23, No. 5, 2004, p. 247-253.

Research output: Contribution to journalArticle

Vokó, Z, Hollander, M, Koudstaal, PJ, Hofman, A & Breteler, MMB 2004, 'How do American stroke risk functions perform in a Western European population?', Neuroepidemiology, vol. 23, no. 5, pp. 247-253. https://doi.org/10.1159/000079951
Vokó, Z. ; Hollander, Monika ; Koudstaal, Peter J. ; Hofman, Albert ; Breteler, Monique M B. / How do American stroke risk functions perform in a Western European population?. In: Neuroepidemiology. 2004 ; Vol. 23, No. 5. pp. 247-253.
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