Homogeneous hydroxyethylation of phenyl-substituted alcohols

Péter Sallay, Mohamed H.M. Ahmed, István Rusznák, László Farkas, Antal Tungler

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Abstract

Homogeneous glycol ether derivatives of phenyl group substituted alcohols (benzyl-, β-phenyl ethyl- and γ-phenyl propyl-) were synthesised by repeated Williamson synthesis starting in two cases from the halogen derivatives of the corresponding alcohols. In the case of β-phenylethanol the first homologue was prepared in the reaction of benzyl group protected ethylene chlorohydrine and β-phenyl-ethyl alcohol. The reaction product was hydrogenolysed (removing the benzyl group by hydrogenolyzis), halogenated and used to the synthesis of higher homologues as starting material.

Original languageEnglish
Pages (from-to)21-26
Number of pages6
JournalACH - Models in Chemistry
Volume133
Issue number1-2
Publication statusPublished - Dec 1 1996

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ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Sallay, P., Ahmed, M. H. M., Rusznák, I., Farkas, L., & Tungler, A. (1996). Homogeneous hydroxyethylation of phenyl-substituted alcohols. ACH - Models in Chemistry, 133(1-2), 21-26.