Histopathological study of major intracranial arteries in premature infants related to intracranial hemorrhage

K. Hegedus, P. Molnár

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The incidence of various types of intracranial hemorrhage (ICH) and the microscopic appearance of the major intracranial arteries were investigated in 112 premature infants, and related to birth weight. In none of the premature newborns, regardless of the presence of ICH, did the intracranial arteries contain true elastic elements. The wall of the basilar artery was significantly thinner in all premature infants with any kind of ICH. Within each body-weight group those with ICH had intracranial arteries with fewer reticular fibers than did those without ICH. The density of the reticular fibers in the cerebral arteries of premature neonates without ICH did not seem to depend on maturity. The authors believe that the hypoplasia of the major intracranial arteries and the reticular fiber deficiency most probably involve the whole vascular system of the brain and may predispose to hemorrhage.

Original languageEnglish
Pages (from-to)419-424
Number of pages6
JournalJournal of Neurosurgery
Volume62
Issue number3
Publication statusPublished - 1985

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Intracranial Hemorrhages
Premature Infants
Arteries
Reticulin
Newborn Infant
Basilar Artery
Cerebral Arteries
Birth Weight
Blood Vessels
Body Weight
Hemorrhage
Incidence
Brain

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Histopathological study of major intracranial arteries in premature infants related to intracranial hemorrhage. / Hegedus, K.; Molnár, P.

In: Journal of Neurosurgery, Vol. 62, No. 3, 1985, p. 419-424.

Research output: Contribution to journalArticle

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