Histopathological diagnosis of postweaning multisystemic wasting syndrome

D. Cadar, V. Miclǎuş, Marina Spînu, V. Rus, A. Cságola, T. Tuboly

Research output: Contribution to journalArticle


Postweaning multisystemic wasting syndrome (PMWS) is a disease of pigs first recognised in North America in 1991 and subsequently reported worldwide that is caused by Porcine circovirus 2 (PCV2), a member of the family Circoviridae. The most consistent feature of PMWS is a generalized depletion of lymphocytes. Secondary infections with opportunistic organisms are common. There is evidence that the destruction of thymic lymphocytes has a central role in the pathogenesis of PMWS.The objective of this paper was to describe the microscopic and ultrastructural pathology associated with natural cases of PCV2, as well as PMWS, a key point in the diagnosis of PCV2 infection and associated diseases.

Original languageEnglish
Pages (from-to)39-44
Number of pages6
JournalAnnals of the Romanian Society for Cell Biology
Issue number1
Publication statusPublished - Dec 1 2009

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

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