In dog liver, perfused in vitro at 4° and 38° C, the following were studied histochemically: the influence of ischemia on non specific alkaline and acid phosphatase, and adenosine triphosphatase and lactate dehydrogenase activity. A 30 min ischemia caused essential changes in enzyme activity. Hypothermic perfusion was the most suitable procedure for liver preservation, although the results obtained under hypothermia without perfusion were almost as good. Histochemical signs of early mitochondrial lesions were frequent.
|Number of pages||14|
|Journal||Acta chirurgica Academiae Scientiarum Hungaricae|
|Publication status||Published - Dec 1 1974|
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