Histochemical techniques revealed that besides the basic similarities between animal and human mast cells the latter differed significantly in the composition of their granules. Biogenic amines failed to be demonstrable and the intensity of the reaction demonstrating the basic protein components referred to a pronounced alkaline ionic balance. The affinity of human mast cells to acid mucopolysaccharide stains differed from that of animal mast cells. From the morphologic characteristics and distribution in the organism of human mast cells, conclusions could be drawn, concerning their origin, circulation in blood paths and localization in connective tissue. Changes in their morphological pattern and occurrence could be explained by the process of their development.
|Number of pages||9|
|Journal||Acta Morphologica Academiae Scientiarum Hungaricae|
|Publication status||Published - 1974|
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