Histamine treatment at neonatal age influences histamine production by peritoneal cells in adult rats

O. Torok, B. Kiss, J. Szeberenyi, Z. Radvany, A. Falus

Research output: Contribution to journalArticle

Abstract

Introduction: Histamine is one of the most important mediators in the mammalian organism. It has a basic role in numerous physiological functions and also in the regulation of cell growth. Material and methods: In the present study the level of cell-bound and secreted histamine was measured in rats exposed to histamine in vivo during their neonatal age or in controls. Results and main conclusions: The findings strongly suggest that the in vivo treatment of neonatal rats with histamine leads to significantly increased level of both spontaneous and histamine-provoked histamine secretion at the age of two months. The results suggest a long-lasting effect of neonatal histamine treatment.

Original languageEnglish
Pages (from-to)1055-1058
Number of pages4
JournalMedical Science Monitor
Volume5
Issue number6
Publication statusPublished - 1999

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Histamine
Growth

Keywords

  • Histamine
  • Neonatal effects
  • Peritoneal cells

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Histamine treatment at neonatal age influences histamine production by peritoneal cells in adult rats. / Torok, O.; Kiss, B.; Szeberenyi, J.; Radvany, Z.; Falus, A.

In: Medical Science Monitor, Vol. 5, No. 6, 1999, p. 1055-1058.

Research output: Contribution to journalArticle

Torok, O. ; Kiss, B. ; Szeberenyi, J. ; Radvany, Z. ; Falus, A. / Histamine treatment at neonatal age influences histamine production by peritoneal cells in adult rats. In: Medical Science Monitor. 1999 ; Vol. 5, No. 6. pp. 1055-1058.
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