The histidine decarboxylase activity in many immunocompetent cells and the relevance of the operation of histamine in the soluble and cellular network of the immune system contributes to fine tuning of the local regulation of inflammation and immune reactions. In addition to the local histamine production, the actual number, type and availability of histamine receptors on various cells of the immune system seems to also contribute to the colourful results of the local and systemic histamine effects. We have been working for many years on the local interaction of histamine with immune reactions. In this review three issues regarding interactions of histamine and the immune response are outlined.
|Number of pages||3|
|Journal||Central-European Journal of Immunology|
|Publication status||Published - Jan 1 1996|
ASJC Scopus subject areas
- Immunology and Allergy