Highly selective palladium-catalyzed aminocarbonylation and cross-coupling reactions on a cavitand scaffold

Zsolt Csók, Anikó Takátsy, László Kollár

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Palladium-catalyzed aminocarbonylation and cross-coupling reactions (Suzuki-, Sonogashira-, Stille-coupling) served as highly efficient synthetic tools for the synthesis of novel, functionalized deepened cavitands. Unexpectedly high chemoselectivities towards tetrafunctionalized cavitands have been observed for all of these reactions even using coupling partners much below the stoichiometric amount. No significant formation of either the mono-, di- or trifunctionalized products was observed.

Original languageEnglish
Pages (from-to)2657-2661
Number of pages5
JournalTetrahedron
Volume68
Issue number12
DOIs
Publication statusPublished - Mar 25 2012

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Keywords

  • Aminocarbonylation
  • Carbon monoxide
  • Cavitand
  • Cross-coupling
  • Palladium

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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