Perifériás biomarkerek depressziós zavarokban: fókuszban a HPA-tengely, az inflammációs rendszer és a neurotrofikus faktorok

Translated title of the contribution: Highlights of peripheral biomarkers in major depressive disorder: focus on HPA-axis, inflammation and neurotrophic factors

Research output: Contribution to journalArticle

Abstract

Investigations intensively focus on peripheral biomarkers in major depressive disorder (MDD), however, an up-to-date amd specific tool is still not available. There is an increasing body of data in the literature concerning this issue and the majority of this confirms that most promising markers are related to the HPA axis, inflammation and neurotrophic factors. Results from the addressed area suggest that testing multiple markers together can provide a valuable outcome in concerning diagnosis, treatment selection and monitoring. Several influencing factors altering the levels of biomarkers as well as biologically inappropriate phenotypic measurements contribute to the numerous difficulties of precise evaluation and validation of biomarkers is. By correcting of these biases clinically applicable lab tests can be developed in the near future which will lead to significant improvement in the personalized therapy of MDD with more successful therapeutic outcomes and it will be an important tool in the pharmaceutical developments too.

Original languageHungarian
Pages (from-to)125-130
Number of pages6
JournalNeuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology
Volume20
Issue number4
Publication statusPublished - Dec 1 2018

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ASJC Scopus subject areas

  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Clinical Neurology

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