High-yielding aminocarbonylation of 3-iodo-2-tropene by using amino acid esters as N-nucleophiles

László Horváth, Z. Berente, L. Kollár

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

3-Iodo-2-tropene, synthesised from the corresponding ketone (tropinone) via its hydrazone, was carbonylated in palladium-catalysed homogeneous aminocarbonylation reactions. The 3-carboxamides containing both the tropene and the aminoacid moieties of biological importance were obtained in chemospecific reactions and isolated in up to 85 % yields.

Original languageEnglish
Pages (from-to)236-238
Number of pages3
JournalLetters in Organic Chemistry
Volume4
Issue number4
DOIs
Publication statusPublished - Jun 2007

Fingerprint

Hydrazones
Nucleophiles
Palladium
Ketones
Esters
Amino Acids
3-tropinone

Keywords

  • Amino acid
  • Carbonylation
  • Homogeneous catalysis
  • Palladium
  • Tropane

ASJC Scopus subject areas

  • Organic Chemistry
  • Biochemistry

Cite this

High-yielding aminocarbonylation of 3-iodo-2-tropene by using amino acid esters as N-nucleophiles. / Horváth, László; Berente, Z.; Kollár, L.

In: Letters in Organic Chemistry, Vol. 4, No. 4, 06.2007, p. 236-238.

Research output: Contribution to journalArticle

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