High-yielding aminocarbonylation of 3-iodo-2-tropene by using amino acid esters as N-nucleophiles

László Horváth, Zoltán Berente, László Kollár

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3-Iodo-2-tropene, synthesised from the corresponding ketone (tropinone) via its hydrazone, was carbonylated in palladium-catalysed homogeneous aminocarbonylation reactions. The 3-carboxamides containing both the tropene and the aminoacid moieties of biological importance were obtained in chemospecific reactions and isolated in up to 85 % yields.

Original languageEnglish
Pages (from-to)236-238
Number of pages3
JournalLetters in Organic Chemistry
Issue number4
Publication statusPublished - Jun 1 2007



  • Amino acid
  • Carbonylation
  • Homogeneous catalysis
  • Palladium
  • Tropane

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

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