High-resolution melting curve analysis to establish CYP2C19*2 single nucleotide polymorphism: Comparison with hydrolysis SNP analysis

Manna Temesvári, József Paulik, László Kóbori, Katalin Monostory

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10 Citations (Scopus)


Clinically significant consequences of CYP2C19 polymorphism in drug metabolism require reliable genotyping methods for assaying large numbers of blood samples. Hydrolysis single nucleotide polymorphism analysis and high-resolution melting curve (HRM) analysis successfully genotyped the 114 liver donors for CYP2C19*2. However, the HRM analysis was found to be more efficient, rapid, user- and cost-friendly method.

Original languageEnglish
Pages (from-to)130-133
Number of pages4
JournalMolecular and Cellular Probes
Issue number2-3
Publication statusPublished - Apr 1 2011



  • CYP2C19*2
  • High-resolution melting curve analysis
  • Hydrolysis SNP analysis
  • Single nucleotide polymorphism

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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