High performance liquid chromatography (hplc) of antibiotics of vancomycin type comparative studies

F. Sztaricskai, R. Bognár, J. Borda, M. M. Puskás

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Comparative HPLC examination of seven antibiotics of vancomycin type has been undertaken. Investigation has shown that on column I in eluent system B, ristomycin A (ristocetin A) can be not only separated from vancomycin, but both antibiotics can be quantitatively determined. Under these conditions the lowest detectable quantities of the individual antibiotics have been also stated. By the application of this column and eluent system A, ristomycin A (ristocetin A) and the major component of the A-35512 B antibiotic complex can be readily separated from one-another and from avoparcin α and β.

Original languageEnglish
Pages (from-to)1691-1698
Number of pages8
JournalJournal of Antibiotics
Volume36
Issue number12
DOIs
Publication statusPublished - Jan 1983

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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