High performance ion chromatography of transition metal chelate complexes and aminopolycarboxylate ligands

Renáta Tófalvi, K. Horváth, Péter Hajós

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A simple ion chromatographic method was developed for the separation of transition metal chelates (CuEDTA, CuDCTA, ZnEDTA, ZnDCTA) and free anionic complexing ligands (EDTA, DCTA) using alkaline carbonate eluents and conductivity detection. The complex equilibria and kinetic process of separations were studied in order to understand major factors in the control of selectivity and retention order of complex anions. A systematic study was applied to identify the additional peaks of the system as NaEDTA3-, NaHEDTA2-, Na2EDTA2-, EDTA4-/HEDTA3-, DCTA4-/HDCTA-3. On the basis of microequilibrium considerations of chelating ligand, it was shown that one should expect the peaks of sodium chelates when the ligand is in excess in the sample solution. The probability density function was introduced for calculation of complex chromatograms, because complexing ligands can exist in at least two different interconvertible forms in the presence of metal ion. The chromatogram of interconverting chelate species can be given as the sum of probability density functions (P) weighed by the molar fractions of complexed (ΦML) and dissociated (ΦL) forms. The influences of kinetic rate of complex formation and dissociation on the distribution of components between eluents and ion exchange stationary phases were quantitatively described and demonstrated by elution profiles. The applicability of the developed method is represented by the simultaneous analysis of transition metal chelates and inorganic anions. ICP-AES analysis and FTIR-ATR technique were used for confirmation of IC results for metals and ligands, respectively. Collection protocols for the heart-cutting procedure of chromatograms were applied in the analysis of target components. The limit of detection and linearity of the method in the range of 0.01-0.25mM sample concentration were also presented.

Original languageEnglish
Pages (from-to)26-32
Number of pages7
JournalJournal of Chromatography A
Volume1272
DOIs
Publication statusPublished - Jan 11 2013

Fingerprint

Ion chromatography
Coordination Complexes
Metal complexes
Transition metals
Chromatography
Ions
Ligands
Metals
Probability density function
Anions
L Forms
Kinetics
Ion Exchange
Carbonates
Fourier Transform Infrared Spectroscopy
Chelation
Edetic Acid
Metal ions
Limit of Detection
Ion exchange

Keywords

  • Chelating ligands
  • Interconvertible forms of complexes
  • Ion chromatography
  • Probability density function for chromatograms
  • Secondary chemical equilibria
  • Transition metal chelate complexes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Organic Chemistry
  • Biochemistry

Cite this

High performance ion chromatography of transition metal chelate complexes and aminopolycarboxylate ligands. / Tófalvi, Renáta; Horváth, K.; Hajós, Péter.

In: Journal of Chromatography A, Vol. 1272, 11.01.2013, p. 26-32.

Research output: Contribution to journalArticle

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