High performance ion chromatography of haloacetic acids on macrocyclic cryptand anion exchanger

Maria Concetta Bruzzoniti, Rosa Maria De Carlo, K. Horváth, Daniela Perrachon, Ambra Prelle, Renáta Tófalvi, Corrado Sarzanini, Péter Hajós

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

A new high performance ion chromatographic method has been developed for the separation of the nine chlorinated-brominated haloacetic acids (HAAs) that are the disinfection by-products of chlorination of drinking water, using a macrocycle-based adjustable-capacity anion-exchange separator column (IonPac Cryptand A1). A gradient method based on theoretical and experimental considerations has been optimized in which 10 mM NaOH-LiOH step gradient was performed at the third minute of the analysis. The optimized method allowed us to separate the nine HAAs and seven possibly interfering inorganic anions in less than 25 min with acceptable resolution. The minimum concentrations detectable for HAAs were between 8.0 (MBA) and 210 (TBA) μg L-1, with linearity included between 0.9947 (TBA) and 0.9998 (MBA). To increase sensitivity, a 25-fold preconcentration step on a reversed phase substrate (LiChrolut EN) has been coupled. Application of this method to the analysis of haloacetic acids in real tap water samples is illustrated.

Original languageEnglish
Pages (from-to)188-196
Number of pages9
JournalJournal of Chromatography A
Volume1187
Issue number1-2
DOIs
Publication statusPublished - Apr 11 2008

Fingerprint

Ion chromatography
Anions
Chromatography
Ions
Acids
Gradient methods
Disinfection
Chlorination
Halogenation
Separators
Drinking Water
Byproducts
cryptand
Water
Substrates

Keywords

  • Disinfection by-products
  • Haloacetic acids
  • Ion chromatography
  • Macrocyclic ligand

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Bruzzoniti, M. C., Carlo, R. M. D., Horváth, K., Perrachon, D., Prelle, A., Tófalvi, R., ... Hajós, P. (2008). High performance ion chromatography of haloacetic acids on macrocyclic cryptand anion exchanger. Journal of Chromatography A, 1187(1-2), 188-196. https://doi.org/10.1016/j.chroma.2008.02.028

High performance ion chromatography of haloacetic acids on macrocyclic cryptand anion exchanger. / Bruzzoniti, Maria Concetta; Carlo, Rosa Maria De; Horváth, K.; Perrachon, Daniela; Prelle, Ambra; Tófalvi, Renáta; Sarzanini, Corrado; Hajós, Péter.

In: Journal of Chromatography A, Vol. 1187, No. 1-2, 11.04.2008, p. 188-196.

Research output: Contribution to journalArticle

Bruzzoniti, MC, Carlo, RMD, Horváth, K, Perrachon, D, Prelle, A, Tófalvi, R, Sarzanini, C & Hajós, P 2008, 'High performance ion chromatography of haloacetic acids on macrocyclic cryptand anion exchanger', Journal of Chromatography A, vol. 1187, no. 1-2, pp. 188-196. https://doi.org/10.1016/j.chroma.2008.02.028
Bruzzoniti, Maria Concetta ; Carlo, Rosa Maria De ; Horváth, K. ; Perrachon, Daniela ; Prelle, Ambra ; Tófalvi, Renáta ; Sarzanini, Corrado ; Hajós, Péter. / High performance ion chromatography of haloacetic acids on macrocyclic cryptand anion exchanger. In: Journal of Chromatography A. 2008 ; Vol. 1187, No. 1-2. pp. 188-196.
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