High incidence of beta-2-microglobulin containing macromolecular complexes in sarcoidosis sera

A. Falus, G. Glikmann, S. E. Svehag

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Abstract

In thirteen out of fourteen sarcoidosis patients with elevated serum levels of immune complexes beta-2-microglobulin (β2m) was detected in immune complex-enriched fractions prepared by precipitation with 3% polyethylene glycol. Beta-2-microglobulin was also contained in complexes isolated by means of solid-phase C1q. The levels of free β2m in sarcoidosis sera did not differ from the concentrations in sera from healthy donors.

Original languageEnglish
Pages (from-to)81-84
Number of pages4
JournalActa Pathologica Microbiologica et Immunologica Scandinavica - Section C Immunology
Volume91
Issue number1
Publication statusPublished - 1983

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Macromolecular Substances
beta 2-Microglobulin
Sarcoidosis
Antigen-Antibody Complex
Incidence
Serum
Tissue Donors

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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abstract = "In thirteen out of fourteen sarcoidosis patients with elevated serum levels of immune complexes beta-2-microglobulin (β2m) was detected in immune complex-enriched fractions prepared by precipitation with 3{\%} polyethylene glycol. Beta-2-microglobulin was also contained in complexes isolated by means of solid-phase C1q. The levels of free β2m in sarcoidosis sera did not differ from the concentrations in sera from healthy donors.",
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AU - Svehag, S. E.

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N2 - In thirteen out of fourteen sarcoidosis patients with elevated serum levels of immune complexes beta-2-microglobulin (β2m) was detected in immune complex-enriched fractions prepared by precipitation with 3% polyethylene glycol. Beta-2-microglobulin was also contained in complexes isolated by means of solid-phase C1q. The levels of free β2m in sarcoidosis sera did not differ from the concentrations in sera from healthy donors.

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