High frequency intergenomic recombination of suid herpesvirus 1 (SHV-1, Aujeszky's disease virus)

L. S. Christensen, B. Lomniczi

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Examples are given of observations made with field isolates of suid herpesvirus 1 (SHV-1) which indicate that intergenomic recombination is a common phenomenon associated with the virus. This was further confirmed by experimental co-infection of a pig with 2 virus strains with different, stable and easily identifiable genomic markers, followed by natural transmission to a group of contact pigs. A variety of recombinants was subsequently isolated, while none of the parental strains were re-isolated from any of the pigs. It is suggested that co-invasion of cells and recombination between viral genomes play a role in the life cycle of the virus.

Original languageEnglish
Pages (from-to)37-50
Number of pages14
JournalArchives of virology
Volume132
Issue number1-2
DOIs
Publication statusPublished - Mar 1 1993

ASJC Scopus subject areas

  • Virology

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