Hierarchical modelling in biology: Systematic building of limb models

C. S. Fazekas, G. Y. Kozmann, K. Hangos

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

A multi-level model, that provides a hierarchically structured description of a complex, multi-scale limb system is proposed in this paper for predicting and analyzing movement patters generated by various activation signals. The levels, the sub-models on each level and their interconnections are developed and described following a systematic modelling procedure. The computational properties (degree of freedom and differential index) of the developed model have been analyzed and a sub-model has been transformed to meet the index-one requirement for solving the resulting differential algebraic equation (DAE) model by standard methods implemented in MATLAB. The model is extensively verified against engineering expectations using parameter values found in the literature, and a good agreement was found. Parameter sensitivity analysis has also been performed.

Original languageEnglish
Title of host publicationIFAC Proceedings Volumes (IFAC-PapersOnline)
Pages49-54
Number of pages6
Volume16
Publication statusPublished - 2005
Event16th Triennial World Congress of International Federation of Automatic Control, IFAC 2005 - Prague, Czech Republic
Duration: Jul 3 2005Jul 8 2005

Other

Other16th Triennial World Congress of International Federation of Automatic Control, IFAC 2005
CountryCzech Republic
CityPrague
Period7/3/057/8/05

Fingerprint

MATLAB
Sensitivity analysis
Differential equations
Chemical activation

Keywords

  • Aponeurosis
  • Biomedical system
  • Hierarchical system
  • Model
  • Muscle
  • Pennation
  • Sarcomere
  • Tendon

ASJC Scopus subject areas

  • Control and Systems Engineering

Cite this

Fazekas, C. S., Kozmann, G. Y., & Hangos, K. (2005). Hierarchical modelling in biology: Systematic building of limb models. In IFAC Proceedings Volumes (IFAC-PapersOnline) (Vol. 16, pp. 49-54)

Hierarchical modelling in biology : Systematic building of limb models. / Fazekas, C. S.; Kozmann, G. Y.; Hangos, K.

IFAC Proceedings Volumes (IFAC-PapersOnline). Vol. 16 2005. p. 49-54.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fazekas, CS, Kozmann, GY & Hangos, K 2005, Hierarchical modelling in biology: Systematic building of limb models. in IFAC Proceedings Volumes (IFAC-PapersOnline). vol. 16, pp. 49-54, 16th Triennial World Congress of International Federation of Automatic Control, IFAC 2005, Prague, Czech Republic, 7/3/05.
Fazekas CS, Kozmann GY, Hangos K. Hierarchical modelling in biology: Systematic building of limb models. In IFAC Proceedings Volumes (IFAC-PapersOnline). Vol. 16. 2005. p. 49-54
Fazekas, C. S. ; Kozmann, G. Y. ; Hangos, K. / Hierarchical modelling in biology : Systematic building of limb models. IFAC Proceedings Volumes (IFAC-PapersOnline). Vol. 16 2005. pp. 49-54
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