Hidden contributors to uncertainty and accuracy of results of residue analysis

A. Ámbrus, Andrea Zentai, Judit Sali, István Ficzere

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Accurate analytical results with known uncertainty are required for the safety assessment of pesticides and testing the conformity of marketed food and feed with the maximum residue limits. The available information on various sources of errors was examined with special emphasis to those which may remain unaccounted for based on the current practice of many laboratories. The method validation typically covers the steps of the pesticide residue determination from the extraction of spiked samples to the instrumental determination, which contribute to only 10-40% of total variance of results. Though the variability of sampling, sample size reduction and sample processing may amount to the 60-90% of total variance, it generally remains unnoticed leading to wrong decisions. Another important source of gross error is the mismatch of the residues analysed and those included in the relevant residue definition. Procedures which may be applied for eliminating or reducing the errors are discussed.

Original languageEnglish
Pages (from-to)3-11
Number of pages9
JournalAccreditation and Quality Assurance
Volume16
Issue number1
DOIs
Publication statusPublished - 2011

Fingerprint

Pesticides
pesticides
Pesticide Residues
food
Sampling
safety
sampling
Testing
Processing
Uncertainty

Keywords

  • Chromatographic analysis
  • Pesticide residues
  • Sample processing
  • Sampling
  • Sources of uncertainty
  • Systematic and gross errors

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)
  • Safety, Risk, Reliability and Quality
  • Instrumentation

Cite this

Hidden contributors to uncertainty and accuracy of results of residue analysis. / Ámbrus, A.; Zentai, Andrea; Sali, Judit; Ficzere, István.

In: Accreditation and Quality Assurance, Vol. 16, No. 1, 2011, p. 3-11.

Research output: Contribution to journalArticle

Ámbrus, A. ; Zentai, Andrea ; Sali, Judit ; Ficzere, István. / Hidden contributors to uncertainty and accuracy of results of residue analysis. In: Accreditation and Quality Assurance. 2011 ; Vol. 16, No. 1. pp. 3-11.
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