Hidden complexity of synaptic receptive fields in cat V1

Julien Fournier, Cyril Monier, Manuel Levy, Olivier Marre, Katalin Sári, Z. Kisvárday, Yves Frégnac

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

In the primary visual cortex (V1), Simple and Complex receptive fields (RFs) are usually characterized on the basis of the linearity of the cell spiking response to stimuli of opposite contrast. Whether or not this classification reflects a functional dichotomy in the synaptic inputs to Simple and Complex cells is still an open issue. Here we combined intracellular membrane potential recordings in cat V1 with 2D dense noise stimulation to decompose the Simple-like and Complex-like components of the subthreshold RF into a parallel set of functionally distinct subunits. Results show that both Simple and Complex RFs exhibit a remarkable diversity of excitatory and inhibitory Complex-like contributions, which differ in orientation and spatial frequency selectivity from the linear RF, even in layer 4 and layer 6 Simple cells. We further show that the diversity of Complex-like contributions recovered at the subthreshold level is expressed in the cell spiking output. These results demonstrate that the Simple or Complex nature of V1 RFs does not rely on the diversity of Complex-like components received by the cell from its synaptic afferents but on the imbalance between the weights of the Simple-like and Complex-like synaptic contributions.

Original languageEnglish
Pages (from-to)5515-5528
Number of pages14
JournalJournal of Neuroscience
Volume34
Issue number16
DOIs
Publication statusPublished - 2014

Fingerprint

Cats
Intracellular Membranes
Visual Cortex
Cellular Structures
Membrane Potentials
Noise
Weights and Measures

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Fournier, J., Monier, C., Levy, M., Marre, O., Sári, K., Kisvárday, Z., & Frégnac, Y. (2014). Hidden complexity of synaptic receptive fields in cat V1. Journal of Neuroscience, 34(16), 5515-5528. https://doi.org/10.1523/JNEUROSCI.0474-13.2014

Hidden complexity of synaptic receptive fields in cat V1. / Fournier, Julien; Monier, Cyril; Levy, Manuel; Marre, Olivier; Sári, Katalin; Kisvárday, Z.; Frégnac, Yves.

In: Journal of Neuroscience, Vol. 34, No. 16, 2014, p. 5515-5528.

Research output: Contribution to journalArticle

Fournier, J, Monier, C, Levy, M, Marre, O, Sári, K, Kisvárday, Z & Frégnac, Y 2014, 'Hidden complexity of synaptic receptive fields in cat V1', Journal of Neuroscience, vol. 34, no. 16, pp. 5515-5528. https://doi.org/10.1523/JNEUROSCI.0474-13.2014
Fournier, Julien ; Monier, Cyril ; Levy, Manuel ; Marre, Olivier ; Sári, Katalin ; Kisvárday, Z. ; Frégnac, Yves. / Hidden complexity of synaptic receptive fields in cat V1. In: Journal of Neuroscience. 2014 ; Vol. 34, No. 16. pp. 5515-5528.
@article{241aa23c13a94bccb799a24a35bd88aa,
title = "Hidden complexity of synaptic receptive fields in cat V1",
abstract = "In the primary visual cortex (V1), Simple and Complex receptive fields (RFs) are usually characterized on the basis of the linearity of the cell spiking response to stimuli of opposite contrast. Whether or not this classification reflects a functional dichotomy in the synaptic inputs to Simple and Complex cells is still an open issue. Here we combined intracellular membrane potential recordings in cat V1 with 2D dense noise stimulation to decompose the Simple-like and Complex-like components of the subthreshold RF into a parallel set of functionally distinct subunits. Results show that both Simple and Complex RFs exhibit a remarkable diversity of excitatory and inhibitory Complex-like contributions, which differ in orientation and spatial frequency selectivity from the linear RF, even in layer 4 and layer 6 Simple cells. We further show that the diversity of Complex-like contributions recovered at the subthreshold level is expressed in the cell spiking output. These results demonstrate that the Simple or Complex nature of V1 RFs does not rely on the diversity of Complex-like components received by the cell from its synaptic afferents but on the imbalance between the weights of the Simple-like and Complex-like synaptic contributions.",
author = "Julien Fournier and Cyril Monier and Manuel Levy and Olivier Marre and Katalin S{\'a}ri and Z. Kisv{\'a}rday and Yves Fr{\'e}gnac",
year = "2014",
doi = "10.1523/JNEUROSCI.0474-13.2014",
language = "English",
volume = "34",
pages = "5515--5528",
journal = "Journal of Neuroscience",
issn = "0270-6474",
publisher = "Society for Neuroscience",
number = "16",

}

TY - JOUR

T1 - Hidden complexity of synaptic receptive fields in cat V1

AU - Fournier, Julien

AU - Monier, Cyril

AU - Levy, Manuel

AU - Marre, Olivier

AU - Sári, Katalin

AU - Kisvárday, Z.

AU - Frégnac, Yves

PY - 2014

Y1 - 2014

N2 - In the primary visual cortex (V1), Simple and Complex receptive fields (RFs) are usually characterized on the basis of the linearity of the cell spiking response to stimuli of opposite contrast. Whether or not this classification reflects a functional dichotomy in the synaptic inputs to Simple and Complex cells is still an open issue. Here we combined intracellular membrane potential recordings in cat V1 with 2D dense noise stimulation to decompose the Simple-like and Complex-like components of the subthreshold RF into a parallel set of functionally distinct subunits. Results show that both Simple and Complex RFs exhibit a remarkable diversity of excitatory and inhibitory Complex-like contributions, which differ in orientation and spatial frequency selectivity from the linear RF, even in layer 4 and layer 6 Simple cells. We further show that the diversity of Complex-like contributions recovered at the subthreshold level is expressed in the cell spiking output. These results demonstrate that the Simple or Complex nature of V1 RFs does not rely on the diversity of Complex-like components received by the cell from its synaptic afferents but on the imbalance between the weights of the Simple-like and Complex-like synaptic contributions.

AB - In the primary visual cortex (V1), Simple and Complex receptive fields (RFs) are usually characterized on the basis of the linearity of the cell spiking response to stimuli of opposite contrast. Whether or not this classification reflects a functional dichotomy in the synaptic inputs to Simple and Complex cells is still an open issue. Here we combined intracellular membrane potential recordings in cat V1 with 2D dense noise stimulation to decompose the Simple-like and Complex-like components of the subthreshold RF into a parallel set of functionally distinct subunits. Results show that both Simple and Complex RFs exhibit a remarkable diversity of excitatory and inhibitory Complex-like contributions, which differ in orientation and spatial frequency selectivity from the linear RF, even in layer 4 and layer 6 Simple cells. We further show that the diversity of Complex-like contributions recovered at the subthreshold level is expressed in the cell spiking output. These results demonstrate that the Simple or Complex nature of V1 RFs does not rely on the diversity of Complex-like components received by the cell from its synaptic afferents but on the imbalance between the weights of the Simple-like and Complex-like synaptic contributions.

UR - http://www.scopus.com/inward/record.url?scp=84899490156&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84899490156&partnerID=8YFLogxK

U2 - 10.1523/JNEUROSCI.0474-13.2014

DO - 10.1523/JNEUROSCI.0474-13.2014

M3 - Article

C2 - 24741042

AN - SCOPUS:84899490156

VL - 34

SP - 5515

EP - 5528

JO - Journal of Neuroscience

JF - Journal of Neuroscience

SN - 0270-6474

IS - 16

ER -