Heterotopic abdominal rat heart transplantation as a model to investigate volume dependency of myocardial remodeling

Kálmán Benke, Alex Ali Sayour, Csaba Mátyás, Bence Ágg, Balázs Tamás Németh, A. Oláh, Mihály Ruppert, István Hartyánszky, Zoltán Szabolcs, Tamás Radovits, B. Merkely, Gábor Szabó

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

Heterotopic abdominal rat heart transplantation has been extensively used to investigate ischemic-reperfusion injury, immunological consequences during heart transplantations and also to study remodeling of the myocardium due to volume unloading.We provide a unique review on the latter and present a summary of the experimental studies on rat heart transplantation to illustrate changes that occur to the myocardiumdue to volume unloading.We divided the literature based on whether normal or failing rat heart models were used. This analysis may provide a basis to understand the physiological effects of mechanical circulatory support therapy.

Original languageEnglish
Pages (from-to)498-505
Number of pages8
JournalTransplantation
Volume101
Issue number3
DOIs
Publication statusPublished - 2017

ASJC Scopus subject areas

  • Transplantation

Fingerprint Dive into the research topics of 'Heterotopic abdominal rat heart transplantation as a model to investigate volume dependency of myocardial remodeling'. Together they form a unique fingerprint.

  • Cite this

    Benke, K., Sayour, A. A., Mátyás, C., Ágg, B., Németh, B. T., Oláh, A., Ruppert, M., Hartyánszky, I., Szabolcs, Z., Radovits, T., Merkely, B., & Szabó, G. (2017). Heterotopic abdominal rat heart transplantation as a model to investigate volume dependency of myocardial remodeling. Transplantation, 101(3), 498-505. https://doi.org/10.1097/TP.0000000000001585