Heterogeneous catalytic 1,4-addition of arylmagnesium compounds to chalcones

Kinga Juhász, Z. Hell

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Abstract

Copper(II) on a 4 Å molecular sieve support catalyses the chemoselective addition of alkyl- and arylmagnesium halides to chalcones. Only the 1,4-addition products were obtained in high yields.

Original languageEnglish
Pages (from-to)3136-3138
Number of pages3
JournalTetrahedron Letters
Volume59
Issue number32
DOIs
Publication statusPublished - Aug 8 2018

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Keywords

  • 1,4-Addition
  • Chalcones
  • Copper
  • Grignard reaction
  • Heterogeneous catalysis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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