A vese orokletes cysticus elvaltozasai

Translated title of the contribution: Hereditary cystic kidney diseases

Research output: Contribution to journalReview article

Abstract

The article is a review on hereditary polycystic kidney diseases with a special attention on their prenatal genetic diagnosis, as ultrasound examination is often not informative in early pregnancy. The genes causing most of these diseases are already isolated, thus direct mutation-analysis is possible. However in practice indirect linkage analysis is widespread, due to its relatively lower demands on work and costs. Autosomal dominant polycystic kidney disease is a common disorder. Its relationship with hypertension makes it of great importance. Prenatal diagnosis is required in families serious manifestations of the disease in early childhood. Autosomal recessive polycystic kidney disease is more scarce, still more frequently diagnosed prenatally. Early prenatal diagnosis is required, because of the fatal outcome of the disease. The other listed polycystic kidney diseases are constituents of multiple malformation syndromes. In familial cases the most important tool of prenatal diagnosis is the molecular genetic examination.

Translated title of the contributionHereditary cystic kidney diseases
Original languageHungarian
Pages (from-to)516-522
Number of pages7
JournalLege Artis Medicinae
Volume9
Issue number7-8
Publication statusPublished - Sep 2 1999

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Hereditary cystic kidney diseases'. Together they form a unique fingerprint.

  • Cite this