Herbal remedies of Solidago - Correlation of phytochemical characteristics and antioxidative properties

P. Apáti, K. Szentmihályi, Sz T. Kristó, I. Papp, P. Vinkler, É Szoke, Á Kéry

Research output: Contribution to journalArticle

105 Citations (Scopus)

Abstract

In this study the correlation of phytochemical characteristics and antioxidative properties of classical herbal tea extracts - Infusum solidaginis, Decoctum solidaginis, Maceratum solidaginis - and tinctures prepared by various concentration of ethanol (40, 70, 96% v/v) have been examined for the release of flavonoids and their antioxidant activity. Quantitative and composition determination of flavonoids were carried out by spectrophotometry, high-performance liquid chromatography and capillary electrophoresis, respectively. Hydrogen-donating ability and reducing power properties were used to define in vitro radical scavenging activity of Solidago extracts, but integral antioxidative capacity was determined by luminometry (Photochem®), calculating the ascorbic acid equivalents. Chlorogenic acid, quercetin-3-O-β-D-rutinoside, quercetin-3-O-β-D-galactoside, quercetin-3-O-β-D-glucoside, quercetin-3-O-β-D-rhamnoside, kaempferol-3-O-α-L-rhamnoside and quercetin were confirmed by retention times and UV spectra. Based on the dissolution rate, variance of flavonoid release and ascorbic acid equivalents it was concluded, that Tinctura solidaginis (70% v/v ethanol) and Infusum solidaginis are the most appropriate preparations.

Original languageEnglish
Pages (from-to)1045-1053
Number of pages9
JournalJournal of Pharmaceutical and Biomedical Analysis
Volume32
Issue number4-5
DOIs
Publication statusPublished - Aug 8 2003

Keywords

  • Classical herbal extracts
  • Flavonoids
  • H-donating activity
  • Integral antioxidative capacity
  • Luminometry
  • Reducing power
  • Solidago canadensis L.

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmaceutical Science
  • Drug Discovery
  • Spectroscopy
  • Clinical Biochemistry

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