A Her2/neu-receptor meghatározás: A betegre szabott terápia egyik alapja emlorákban

Translated title of the contribution: Her2/neu receptor: One of the basic factors rendering tailored therapy feasible in breast cancer patients

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

In a considerable part of breast carcinomas the amount of cell surface Her2/neu receptors has been increased such that it becomes the main factor defining the behaviour of the tumor. At the same time, in such amount, this receptor is easily detectable by simple, routine pathological methods. If we are aware of the exact biological characteristics of a given tumor, targeted therapy may be used since an antibody against the Her2 receptor is already available. This drug, called trastuzumab (Herceptin), has been used in advanced breast carcinoma as adjuvant or primary treatment. In clinical trials its advantage in early stage breast carcinomas has been investigated so far.

Original languageHungarian
Pages (from-to)785-790
Number of pages6
JournalOrvosi hetilap
Volume146
Issue number17
Publication statusPublished - Dec 1 2005

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ASJC Scopus subject areas

  • Medicine(all)

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