Hepatitis C-vírus RNA jelenléte krónikus C-hepatitishez társult prurigóban.

Translated title of the contribution: Hepatitis C virus RNA in the skin eruption from patients with prurigo and chronic hepatitis C

Beáta Podányi, András Kiss, Pál Kaposi Novák, C. Páska, G. Lengyel, M. Horányi, Z. Schaff, A. Horváth

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Hepatitis C virus RNA in the skin eruption from patients with prurigo and chronic hepatitis C. Since the discovery of hepatitis C virus (HCV) in 1989, many cutaneous disorders have been observed in patients suffering from chronic HCV infection. The relationship between HCV infection and cryoglobulinemia and porphyria cutanea tarda is clearly established, however, the link between HCV and other skin diseases is still controversial. AIM: Two patients with intense pruritus and secondary prurigo in chronic C hepatitis have been presented. METHODS: The chronic hepatitis C of the patients were proved by elevated ALT and AST level, anti HCV (ELISA), HCV-PCR serological examination and liver biopsy. The skin lesions were accompanied by severe itching. According to clinical symptoms the patients suffered from prurigo simplex. RESULTS: HCV RNA in the skin specimen from the biopsy of the skin lesion was detected by RT PCR method, but the non affected skin specimen from the patients was HCV RNA negative. CONCLUSIONS: This report is a case of prurigo simplex with chronic C hepatitis proving a direct relation between the HCV infection and prurigo.

Original languageHungarian
Pages (from-to)2371-2374
Number of pages4
JournalOrvosi Hetilap
Volume145
Issue number47
Publication statusPublished - Nov 21 2004

Fingerprint

Prurigo
Chronic Hepatitis C
Hepacivirus
RNA
Skin
Virus Diseases
Pruritus
Porphyria Cutanea Tarda
Biopsy
Cryoglobulinemia
Polymerase Chain Reaction
Skin Diseases
Enzyme-Linked Immunosorbent Assay

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hepatitis C-vírus RNA jelenléte krónikus C-hepatitishez társult prurigóban. / Podányi, Beáta; Kiss, András; Kaposi Novák, Pál; Páska, C.; Lengyel, G.; Horányi, M.; Schaff, Z.; Horváth, A.

In: Orvosi Hetilap, Vol. 145, No. 47, 21.11.2004, p. 2371-2374.

Research output: Contribution to journalArticle

@article{52936f28309844e6bc0f1d22a12cba91,
title = "Hepatitis C-v{\'i}rus RNA jelenl{\'e}te kr{\'o}nikus C-hepatitishez t{\'a}rsult prurig{\'o}ban.",
abstract = "Hepatitis C virus RNA in the skin eruption from patients with prurigo and chronic hepatitis C. Since the discovery of hepatitis C virus (HCV) in 1989, many cutaneous disorders have been observed in patients suffering from chronic HCV infection. The relationship between HCV infection and cryoglobulinemia and porphyria cutanea tarda is clearly established, however, the link between HCV and other skin diseases is still controversial. AIM: Two patients with intense pruritus and secondary prurigo in chronic C hepatitis have been presented. METHODS: The chronic hepatitis C of the patients were proved by elevated ALT and AST level, anti HCV (ELISA), HCV-PCR serological examination and liver biopsy. The skin lesions were accompanied by severe itching. According to clinical symptoms the patients suffered from prurigo simplex. RESULTS: HCV RNA in the skin specimen from the biopsy of the skin lesion was detected by RT PCR method, but the non affected skin specimen from the patients was HCV RNA negative. CONCLUSIONS: This report is a case of prurigo simplex with chronic C hepatitis proving a direct relation between the HCV infection and prurigo.",
author = "Be{\'a}ta Pod{\'a}nyi and Andr{\'a}s Kiss and {Kaposi Nov{\'a}k}, P{\'a}l and C. P{\'a}ska and G. Lengyel and M. Hor{\'a}nyi and Z. Schaff and A. Horv{\'a}th",
year = "2004",
month = "11",
day = "21",
language = "Hungarian",
volume = "145",
pages = "2371--2374",
journal = "Orvosi Hetilap",
issn = "0030-6002",
publisher = "Akademiai Kiado",
number = "47",

}

TY - JOUR

T1 - Hepatitis C-vírus RNA jelenléte krónikus C-hepatitishez társult prurigóban.

AU - Podányi, Beáta

AU - Kiss, András

AU - Kaposi Novák, Pál

AU - Páska, C.

AU - Lengyel, G.

AU - Horányi, M.

AU - Schaff, Z.

AU - Horváth, A.

PY - 2004/11/21

Y1 - 2004/11/21

N2 - Hepatitis C virus RNA in the skin eruption from patients with prurigo and chronic hepatitis C. Since the discovery of hepatitis C virus (HCV) in 1989, many cutaneous disorders have been observed in patients suffering from chronic HCV infection. The relationship between HCV infection and cryoglobulinemia and porphyria cutanea tarda is clearly established, however, the link between HCV and other skin diseases is still controversial. AIM: Two patients with intense pruritus and secondary prurigo in chronic C hepatitis have been presented. METHODS: The chronic hepatitis C of the patients were proved by elevated ALT and AST level, anti HCV (ELISA), HCV-PCR serological examination and liver biopsy. The skin lesions were accompanied by severe itching. According to clinical symptoms the patients suffered from prurigo simplex. RESULTS: HCV RNA in the skin specimen from the biopsy of the skin lesion was detected by RT PCR method, but the non affected skin specimen from the patients was HCV RNA negative. CONCLUSIONS: This report is a case of prurigo simplex with chronic C hepatitis proving a direct relation between the HCV infection and prurigo.

AB - Hepatitis C virus RNA in the skin eruption from patients with prurigo and chronic hepatitis C. Since the discovery of hepatitis C virus (HCV) in 1989, many cutaneous disorders have been observed in patients suffering from chronic HCV infection. The relationship between HCV infection and cryoglobulinemia and porphyria cutanea tarda is clearly established, however, the link between HCV and other skin diseases is still controversial. AIM: Two patients with intense pruritus and secondary prurigo in chronic C hepatitis have been presented. METHODS: The chronic hepatitis C of the patients were proved by elevated ALT and AST level, anti HCV (ELISA), HCV-PCR serological examination and liver biopsy. The skin lesions were accompanied by severe itching. According to clinical symptoms the patients suffered from prurigo simplex. RESULTS: HCV RNA in the skin specimen from the biopsy of the skin lesion was detected by RT PCR method, but the non affected skin specimen from the patients was HCV RNA negative. CONCLUSIONS: This report is a case of prurigo simplex with chronic C hepatitis proving a direct relation between the HCV infection and prurigo.

UR - http://www.scopus.com/inward/record.url?scp=13744255454&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=13744255454&partnerID=8YFLogxK

M3 - Article

C2 - 15641669

AN - SCOPUS:13744255454

VL - 145

SP - 2371

EP - 2374

JO - Orvosi Hetilap

JF - Orvosi Hetilap

SN - 0030-6002

IS - 47

ER -