Hepatitis C virus genotypes in Hungarian and Austrian patients with chronic hepatitis C

Zsófia Müller, Judith Deák, R. Stefan Ross, E. Nagy, László Kovács, M. Roggendorf, Harald H. Kessler

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Hepatitis C virus (HCV) genotypes are relevant to epidemiological questions, vaccine development, and clinical management of chronic HCV infection. The aim of this study was to determine HCV genotypes of South Hungarian and Southeast Austrian patients with chronic hepatitis C. Results were obtained by the largely automated TruGene HCV 5′NC Genotyping Kit (Visible Genetics, Toronto, Ontario) and by phylogenetic analysis. All of the 20 Hungarian patients and 15 out of 20 Austrian patients were infected with genotype 1. The remaining Austrian patients were infected with genotypes 3 or 2. With the commercially available assay, it was not possible to determine the HCV subtype in a total of three patients. The TruGene HCV 5′NC Genotyping assay for the determination of HCV genotypes proved to be useful for a high-throughput routine diagnostic laboratory.

Original languageEnglish
Pages (from-to)295-300
Number of pages6
JournalJournal of Clinical Virology
Volume26
Issue number3
DOIs
Publication statusPublished - Apr 2003

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Chronic Hepatitis C
Hepacivirus
Genotype
Ontario
Virus Diseases
Vaccines

Keywords

  • Austria
  • Genotype
  • HCV
  • Hungary
  • Sequencing

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Virology
  • Immunology and Allergy
  • Infectious Diseases

Cite this

Hepatitis C virus genotypes in Hungarian and Austrian patients with chronic hepatitis C. / Müller, Zsófia; Deák, Judith; Ross, R. Stefan; Nagy, E.; Kovács, László; Roggendorf, M.; Kessler, Harald H.

In: Journal of Clinical Virology, Vol. 26, No. 3, 04.2003, p. 295-300.

Research output: Contribution to journalArticle

Müller, Z, Deák, J, Ross, RS, Nagy, E, Kovács, L, Roggendorf, M & Kessler, HH 2003, 'Hepatitis C virus genotypes in Hungarian and Austrian patients with chronic hepatitis C', Journal of Clinical Virology, vol. 26, no. 3, pp. 295-300. https://doi.org/10.1016/S1386-6532(02)00045-8
Müller, Zsófia ; Deák, Judith ; Ross, R. Stefan ; Nagy, E. ; Kovács, László ; Roggendorf, M. ; Kessler, Harald H. / Hepatitis C virus genotypes in Hungarian and Austrian patients with chronic hepatitis C. In: Journal of Clinical Virology. 2003 ; Vol. 26, No. 3. pp. 295-300.
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