Hepatitis B surface antigen circulating immune complexes (HBsAg-CICs) in patients with bleeding disorders

N. Anh-Tuan, E. Novak, S. Hollán

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Approximately 90% of 67 multi-transfused patients with bleeding disorders were positive either for anti-HBs (85%) or HBsAg (4.5%). Using a polyethylene glycol trypsinization assay, we found HBsAg-containing specific circulating immune complexes (HBsAg-CICs) in 3 of the 57 HBsAg-negative haemophiliacs possessing anti-HBs. The occurrence of HBsAg-CICs may be a regular event in the conversion phase of HBs infection. Circulating immune complexes as detected by the anticomplementary assay were found in 32 of the 67 (48%) patients.

Original languageEnglish
Pages (from-to)12-16
Number of pages5
JournalVox Sanguinis
Volume40
Issue number1
Publication statusPublished - 1981

Fingerprint

Hepatitis B Surface Antigens
Antigen-Antibody Complex
Hemorrhage
Infection

ASJC Scopus subject areas

  • Hematology

Cite this

Hepatitis B surface antigen circulating immune complexes (HBsAg-CICs) in patients with bleeding disorders. / Anh-Tuan, N.; Novak, E.; Hollán, S.

In: Vox Sanguinis, Vol. 40, No. 1, 1981, p. 12-16.

Research output: Contribution to journalArticle

@article{0a86cd5c57fc4b8696a8cc9ea8515acc,
title = "Hepatitis B surface antigen circulating immune complexes (HBsAg-CICs) in patients with bleeding disorders",
abstract = "Approximately 90{\%} of 67 multi-transfused patients with bleeding disorders were positive either for anti-HBs (85{\%}) or HBsAg (4.5{\%}). Using a polyethylene glycol trypsinization assay, we found HBsAg-containing specific circulating immune complexes (HBsAg-CICs) in 3 of the 57 HBsAg-negative haemophiliacs possessing anti-HBs. The occurrence of HBsAg-CICs may be a regular event in the conversion phase of HBs infection. Circulating immune complexes as detected by the anticomplementary assay were found in 32 of the 67 (48{\%}) patients.",
author = "N. Anh-Tuan and E. Novak and S. Holl{\'a}n",
year = "1981",
language = "English",
volume = "40",
pages = "12--16",
journal = "Vox Sanguinis",
issn = "0042-9007",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Hepatitis B surface antigen circulating immune complexes (HBsAg-CICs) in patients with bleeding disorders

AU - Anh-Tuan, N.

AU - Novak, E.

AU - Hollán, S.

PY - 1981

Y1 - 1981

N2 - Approximately 90% of 67 multi-transfused patients with bleeding disorders were positive either for anti-HBs (85%) or HBsAg (4.5%). Using a polyethylene glycol trypsinization assay, we found HBsAg-containing specific circulating immune complexes (HBsAg-CICs) in 3 of the 57 HBsAg-negative haemophiliacs possessing anti-HBs. The occurrence of HBsAg-CICs may be a regular event in the conversion phase of HBs infection. Circulating immune complexes as detected by the anticomplementary assay were found in 32 of the 67 (48%) patients.

AB - Approximately 90% of 67 multi-transfused patients with bleeding disorders were positive either for anti-HBs (85%) or HBsAg (4.5%). Using a polyethylene glycol trypsinization assay, we found HBsAg-containing specific circulating immune complexes (HBsAg-CICs) in 3 of the 57 HBsAg-negative haemophiliacs possessing anti-HBs. The occurrence of HBsAg-CICs may be a regular event in the conversion phase of HBs infection. Circulating immune complexes as detected by the anticomplementary assay were found in 32 of the 67 (48%) patients.

UR - http://www.scopus.com/inward/record.url?scp=0019523272&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019523272&partnerID=8YFLogxK

M3 - Article

C2 - 6971526

AN - SCOPUS:0019523272

VL - 40

SP - 12

EP - 16

JO - Vox Sanguinis

JF - Vox Sanguinis

SN - 0042-9007

IS - 1

ER -