The authors studied the effect of fetomaternal transfusion after 686 genetic amniocentesis. The extent of fetomaternal transfusion was calculated on the basis of the maternal serum alpha-fetoprotein levels before and after the procedures. The fetal heart rate and resistance index was measured in the umbilical cord. Inverse correlation was found between the fetal heart frequency and the amount of fetomaternal transfusion (r=0.16; p<0.0001 ). The pregnants were divided into two groups concerning the fetal heart frequency. The fetal heart frequency was decreased after the procedure in Group-A, whereas in Group-B the heart frequency was not changed or elevated. Two-hundred and fifty-seven pregnants got into Group-A, and 429 into Group-B. The mean fetomaternal transfusion was 26 μl in Group-A and 11 μl in Group-B (p<0.01). Fetomaternal transfusion over 200 μl was occurred in 14 (5.4%) cases in Group-A, and in 3 (0.7%) cases in Group-B (OR:8.2; 95% CI:2.3-28.7; p<0.001). There was no significant difference in the outcome of pregnancies between Group-A and Group-B. Correlation was not found between the amount of fetomaternal transfusion and the resistance index. They conclude that higher amount of fetomaternal transfusion (200 μl or more) may cause fetal hart rate deceleration. This fetal hart rate deceleration did not have any unfavourable effect on the outcome of pregnancies.
|Translated title of the contribution||Hemodinamic changes in the fetomaternal circulation caused by fetomaternal transfusion after amniocentesis|
|Number of pages||10|
|Journal||Magyar Noorvosok Lapja|
|Publication status||Published - Nov 17 2006|
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynaecology