Hemigonadectomy induced unilateral changes in the protein synthesizing activity of the rat hypothalamic arcuate nucleus

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

The effect of unilateral ovariectomy on the protein synthesizing activity of the hypothalamic arcuate and dorsomedial nucleus on both sides was studied in vivo as well as in vitro. Four weeks after the removal of 1 ovary, there was a significant increase in labelled amino acid incorporated into the arcuate neurons contralateral to the removed ovary as compared to those incorporated into the nerve cells of the nucleus on the ipsilateral side. In the dorsomedial nucleus, there was no difference between the 2 sides. On the basis of the present findings, the existence of a neural pathway between the ovary and the hypothalamic arcuate nucleus is assumed.

Original languageEnglish
Pages (from-to)331-337
Number of pages7
JournalNeuroendocrinology
Volume21
Issue number4
Publication statusPublished - 1976

Fingerprint

Arcuate Nucleus of Hypothalamus
Ovary
Mediodorsal Thalamic Nucleus
Neurons
Neural Pathways
Proteins
Ovariectomy
Cell Nucleus
Amino Acids

ASJC Scopus subject areas

  • Endocrinology
  • Neuroscience(all)

Cite this

@article{6d3fd24935fd4f3d946d63dd12c522ab,
title = "Hemigonadectomy induced unilateral changes in the protein synthesizing activity of the rat hypothalamic arcuate nucleus",
abstract = "The effect of unilateral ovariectomy on the protein synthesizing activity of the hypothalamic arcuate and dorsomedial nucleus on both sides was studied in vivo as well as in vitro. Four weeks after the removal of 1 ovary, there was a significant increase in labelled amino acid incorporated into the arcuate neurons contralateral to the removed ovary as compared to those incorporated into the nerve cells of the nucleus on the ipsilateral side. In the dorsomedial nucleus, there was no difference between the 2 sides. On the basis of the present findings, the existence of a neural pathway between the ovary and the hypothalamic arcuate nucleus is assumed.",
author = "I. Gerendai and B. Hal{\'a}sz",
year = "1976",
language = "English",
volume = "21",
pages = "331--337",
journal = "Neuroendocrinology",
issn = "0028-3835",
publisher = "S. Karger AG",
number = "4",

}

TY - JOUR

T1 - Hemigonadectomy induced unilateral changes in the protein synthesizing activity of the rat hypothalamic arcuate nucleus

AU - Gerendai, I.

AU - Halász, B.

PY - 1976

Y1 - 1976

N2 - The effect of unilateral ovariectomy on the protein synthesizing activity of the hypothalamic arcuate and dorsomedial nucleus on both sides was studied in vivo as well as in vitro. Four weeks after the removal of 1 ovary, there was a significant increase in labelled amino acid incorporated into the arcuate neurons contralateral to the removed ovary as compared to those incorporated into the nerve cells of the nucleus on the ipsilateral side. In the dorsomedial nucleus, there was no difference between the 2 sides. On the basis of the present findings, the existence of a neural pathway between the ovary and the hypothalamic arcuate nucleus is assumed.

AB - The effect of unilateral ovariectomy on the protein synthesizing activity of the hypothalamic arcuate and dorsomedial nucleus on both sides was studied in vivo as well as in vitro. Four weeks after the removal of 1 ovary, there was a significant increase in labelled amino acid incorporated into the arcuate neurons contralateral to the removed ovary as compared to those incorporated into the nerve cells of the nucleus on the ipsilateral side. In the dorsomedial nucleus, there was no difference between the 2 sides. On the basis of the present findings, the existence of a neural pathway between the ovary and the hypothalamic arcuate nucleus is assumed.

UR - http://www.scopus.com/inward/record.url?scp=0017048842&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017048842&partnerID=8YFLogxK

M3 - Article

C2 - 1021714

AN - SCOPUS:0017048842

VL - 21

SP - 331

EP - 337

JO - Neuroendocrinology

JF - Neuroendocrinology

SN - 0028-3835

IS - 4

ER -