Helicobacter pylori and molecular mechanisms of gastric carcinogenesis: Targets for prevention and therapy

Márk Juhász, L. Herszényi, Z. Tulassay, Peter Malfertheiner, Matthias P A Ebert

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Gastric cancer is still a leading cause of cancer death worldwide. It is frequently diagnosed an advanced stage and the overall prognosis is dismal. A major improvement will only be reached with a better understanding of the genetic changes underlying gastric cancer, which may provide us with effective prevention and treatment strategies. This review will highlight the present knowledge on the role of Helicobacter pylori in gastric carcinogenesis and the molecular pathogenesis of gastric cancer, as well as provide a brief overview of possible future targets for more specific and successful treatment options.

Original languageEnglish
Pages (from-to)97-103
Number of pages7
JournalExpert Review of Anticancer Therapy
Volume4
Issue number1
Publication statusPublished - Feb 2004

Fingerprint

Helicobacter pylori
Stomach Neoplasms
Stomach
Carcinogenesis
Cause of Death
Therapeutics
Neoplasms

Keywords

  • Angiogenesis
  • Apoptosis
  • Cyclooxygenase-2
  • Gastric cancer
  • Gene therapy
  • Growth factor
  • Helicobacter pylori
  • Prevention
  • Therapy

ASJC Scopus subject areas

  • Pharmacology
  • Cancer Research

Cite this

Helicobacter pylori and molecular mechanisms of gastric carcinogenesis : Targets for prevention and therapy. / Juhász, Márk; Herszényi, L.; Tulassay, Z.; Malfertheiner, Peter; Ebert, Matthias P A.

In: Expert Review of Anticancer Therapy, Vol. 4, No. 1, 02.2004, p. 97-103.

Research output: Contribution to journalArticle

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