Haemorrhagic nephritis and enteritis of geese

Pathomorphological investigations and proposed pathogenesis

M. Dobos-Kovács, E. Horváth, A. Farsang, Edith Nagy, Andrea Kovács, F. Szalai, S. Bernáth

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Haemorrhagic nephritis and enteritis of geese as a new disease was first described in Hungary in 1969. The authors identified the causative agent of the outbreaks occurring in 1969 as a polyomavirus by PCR in 2001. In order to study the pathogenesis of the virus, one-day-old goslings were infected with tissue homogenate that tested positive for polyomavirus by PCR. Morphological, light and transmission electron microscopic (TEM) examinations have revealed that goose haemorrhagic polyomavirus replicates in the endothelial cells of the blood vessels and capillaries of diseased birds. Infection causes damage and necrosis of the endothelial cells. The virus was not observed in the parenchymal cells. Oedema and haemorrhages found throughout the body may be due to the dysfunction or functional deficiency of endothelial cells damaged by the virus.

Original languageEnglish
Pages (from-to)213-223
Number of pages11
JournalActa Veterinaria Hungarica
Volume53
Issue number2
DOIs
Publication statusPublished - 2005

Fingerprint

Polyomavirus
Geese
nephritis
Enteritis
Nephritis
enteritis
geese
endothelial cells
pathogenesis
Endothelial Cells
Viruses
viruses
Bird Diseases
goslings
blood capillaries
Polymerase Chain Reaction
Hungary
blood vessels
edema
hemorrhage

Keywords

  • Electron microscopy
  • Haemorrhagic enteritis and nephritis of geese
  • Pathogenesis

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Haemorrhagic nephritis and enteritis of geese : Pathomorphological investigations and proposed pathogenesis. / Dobos-Kovács, M.; Horváth, E.; Farsang, A.; Nagy, Edith; Kovács, Andrea; Szalai, F.; Bernáth, S.

In: Acta Veterinaria Hungarica, Vol. 53, No. 2, 2005, p. 213-223.

Research output: Contribution to journalArticle

Dobos-Kovács, M. ; Horváth, E. ; Farsang, A. ; Nagy, Edith ; Kovács, Andrea ; Szalai, F. ; Bernáth, S. / Haemorrhagic nephritis and enteritis of geese : Pathomorphological investigations and proposed pathogenesis. In: Acta Veterinaria Hungarica. 2005 ; Vol. 53, No. 2. pp. 213-223.
@article{76c5e15fc3454936952423d7b2d91c57,
title = "Haemorrhagic nephritis and enteritis of geese: Pathomorphological investigations and proposed pathogenesis",
abstract = "Haemorrhagic nephritis and enteritis of geese as a new disease was first described in Hungary in 1969. The authors identified the causative agent of the outbreaks occurring in 1969 as a polyomavirus by PCR in 2001. In order to study the pathogenesis of the virus, one-day-old goslings were infected with tissue homogenate that tested positive for polyomavirus by PCR. Morphological, light and transmission electron microscopic (TEM) examinations have revealed that goose haemorrhagic polyomavirus replicates in the endothelial cells of the blood vessels and capillaries of diseased birds. Infection causes damage and necrosis of the endothelial cells. The virus was not observed in the parenchymal cells. Oedema and haemorrhages found throughout the body may be due to the dysfunction or functional deficiency of endothelial cells damaged by the virus.",
keywords = "Electron microscopy, Haemorrhagic enteritis and nephritis of geese, Pathogenesis",
author = "M. Dobos-Kov{\'a}cs and E. Horv{\'a}th and A. Farsang and Edith Nagy and Andrea Kov{\'a}cs and F. Szalai and S. Bern{\'a}th",
year = "2005",
doi = "10.1556/AVet.53.2005.2.6",
language = "English",
volume = "53",
pages = "213--223",
journal = "Acta Veterinaria Hungarica",
issn = "0236-6290",
publisher = "Akademiai Kiado",
number = "2",

}

TY - JOUR

T1 - Haemorrhagic nephritis and enteritis of geese

T2 - Pathomorphological investigations and proposed pathogenesis

AU - Dobos-Kovács, M.

AU - Horváth, E.

AU - Farsang, A.

AU - Nagy, Edith

AU - Kovács, Andrea

AU - Szalai, F.

AU - Bernáth, S.

PY - 2005

Y1 - 2005

N2 - Haemorrhagic nephritis and enteritis of geese as a new disease was first described in Hungary in 1969. The authors identified the causative agent of the outbreaks occurring in 1969 as a polyomavirus by PCR in 2001. In order to study the pathogenesis of the virus, one-day-old goslings were infected with tissue homogenate that tested positive for polyomavirus by PCR. Morphological, light and transmission electron microscopic (TEM) examinations have revealed that goose haemorrhagic polyomavirus replicates in the endothelial cells of the blood vessels and capillaries of diseased birds. Infection causes damage and necrosis of the endothelial cells. The virus was not observed in the parenchymal cells. Oedema and haemorrhages found throughout the body may be due to the dysfunction or functional deficiency of endothelial cells damaged by the virus.

AB - Haemorrhagic nephritis and enteritis of geese as a new disease was first described in Hungary in 1969. The authors identified the causative agent of the outbreaks occurring in 1969 as a polyomavirus by PCR in 2001. In order to study the pathogenesis of the virus, one-day-old goslings were infected with tissue homogenate that tested positive for polyomavirus by PCR. Morphological, light and transmission electron microscopic (TEM) examinations have revealed that goose haemorrhagic polyomavirus replicates in the endothelial cells of the blood vessels and capillaries of diseased birds. Infection causes damage and necrosis of the endothelial cells. The virus was not observed in the parenchymal cells. Oedema and haemorrhages found throughout the body may be due to the dysfunction or functional deficiency of endothelial cells damaged by the virus.

KW - Electron microscopy

KW - Haemorrhagic enteritis and nephritis of geese

KW - Pathogenesis

UR - http://www.scopus.com/inward/record.url?scp=19944424832&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=19944424832&partnerID=8YFLogxK

U2 - 10.1556/AVet.53.2005.2.6

DO - 10.1556/AVet.53.2005.2.6

M3 - Article

VL - 53

SP - 213

EP - 223

JO - Acta Veterinaria Hungarica

JF - Acta Veterinaria Hungarica

SN - 0236-6290

IS - 2

ER -