A hemolitikus urémiás szindróma és a trombotiks thrombocytopeniás purpura molekuláris szemléletu klasszifikációja és diagnosztikájuknak aktuális kérdései

Translated title of the contribution: Haemolytic uremic syndrome and thrombotic thrombocytopenic purpura: Classification based on molecular etiology and review on recent development of diagnostics

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Haemolytic uremic syndrome and thrombotic thrombocytopenic purpura are overlapping clinical entities based on historical classification. Recent developments in the unfolding of the pathomechanisms of these diseases resulted in the creation of a molecular etiology-based classification. Understanding of some causative relationships yielded detailed diagnostic approaches, novel therapeutic options and thorough prognostic assortment of the patients. Although haemolytic uremic syndrome and thrombotic thrombocytopenic purpura are rare diseases with poor prognosis, the precise molecular etiology-based diagnosis might properly direct the therapy of the affected patients. The current review focuses on the theoretical background and detailed description of the available diagnostic possibilities, and some practical information necessary for the interpretation of their results.

Translated title of the contributionHaemolytic uremic syndrome and thrombotic thrombocytopenic purpura: Classification based on molecular etiology and review on recent development of diagnostics
Original languageHungarian
Pages (from-to)1251-1261
Number of pages11
JournalOrvosi hetilap
Volume149
Issue number27
DOIs
Publication statusPublished - Jul 6 2008

ASJC Scopus subject areas

  • Medicine(all)

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