Haemodynamic changes induced by intrasaccular packing on intracranial aneurysms

A computational fluid dynamic study

Ádám Ugron, I. Szikora, György Paál

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Endovascular treatment of intracranial aneurysms is a routine medical practice. The most widely used technique is the packing the aneurysm sac with an embolic material. To gain deeper understanding in the effects of specific treatment methods, the intra-aneurysmal haemodynamics are studied with the help of patient-specific computational models. Numerical simulations demonstrated that embolisation with liquid polymer results in an overall decrease of the wall shear stress and pressure in the aneurysm region. Within the range of clinically relevant packing density, simulation of coil embolisation showed homogenisation and decrease of the wall loads on the aneurysm sac. Increasing the packing density above 20% produces little or no further reduction of intra-aneurysmal flow. Sufficient packing of the aneurysm sac results in significant intra-aneurysmal flow decrease associated with reduced wall loads but locally increased pressure or wall shear stress zones may appear depending on the specific vessel geometry.

Original languageEnglish
Pages (from-to)78-84
Number of pages7
JournalInterventional Medicine and Applied Science
Volume4
Issue number2
DOIs
Publication statusPublished - Jun 1 2012

Fingerprint

Intracranial Aneurysm
Hydrodynamics
Aneurysm
Hemodynamics
Pressure
Polymers
Therapeutics

Keywords

  • coil embolisation
  • endovascular treatment
  • intracranial aneurysm
  • liquid polymer embolisation
  • packing density
  • patient-specific simulation
  • wall shear stress

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Haemodynamic changes induced by intrasaccular packing on intracranial aneurysms : A computational fluid dynamic study. / Ugron, Ádám; Szikora, I.; Paál, György.

In: Interventional Medicine and Applied Science, Vol. 4, No. 2, 01.06.2012, p. 78-84.

Research output: Contribution to journalArticle

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