Authors' synopsis: In closed-chest anaesthetized dogs subjected to moderate and severe haemorrhage (mean blood pressures of 70-75 and 45-50 mm Hg respectively), the administration of oxygen at 2 ATA (OHP) failed to modify the decreases in cardiac output, work, eficiency, and myocardial oxygen consumption that result from blood loss. OHP further decreased myocardial bloodflow in these hypotensive dogs and, despite the marked increases in arterial oxygen tension, myocardial oxygen availability was not improved.
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Physiology (medical)