Haemodynamic and myocardial effects of hyperbaric oxygen in dogs subjected to haemorrhage

I. Mca Ledingham, J. Parratt, G. Smith, J. P. Vance

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Authors' synopsis: In closed-chest anaesthetized dogs subjected to moderate and severe haemorrhage (mean blood pressures of 70-75 and 45-50 mm Hg respectively), the administration of oxygen at 2 ATA (OHP) failed to modify the decreases in cardiac output, work, eficiency, and myocardial oxygen consumption that result from blood loss. OHP further decreased myocardial bloodflow in these hypotensive dogs and, despite the marked increases in arterial oxygen tension, myocardial oxygen availability was not improved.

Original languageEnglish
Pages (from-to)277-285
Number of pages9
JournalCardiovascular Research
Volume5
Issue number3
DOIs
Publication statusPublished - Jan 1 1971

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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