Growth signalling pathways in Arabidopsis and the AGC protein kinases

László Bögre, L. Ökrész, Rossana Henriques, Richard G. Anthony

Research output: Contribution to journalArticle

141 Citations (Scopus)

Abstract

Lipid-derived signals are central to regulating a multitude of cellular processes but, in plants, little is known of the downstream signalling pathways. The Arabidopsis 3-phosphoinositide-dependent protein kinase (PDK1) could couple lipid signals to the activation of several protein kinases of the so-called AGC kinase family. The Arabidopsis AGC kinases contain sequence motives required for the docking of PDK1 and phosphorylation of their activation loop in the kinase catalytic domain. It is becoming evident that specific members of the AGC kinases are implicated in key growth signalling pathways. For example, Arabidopsis p70S6K might be a nodal point able to integrate hormonal and developmental signals with nutritional inputs, together with the Arabidopsis Target of Rapamycin (TOR) protein.

Original languageEnglish
Pages (from-to)424-431
Number of pages8
JournalTrends in Plant Science
Volume8
Issue number9
DOIs
Publication statusPublished - Sep 1 2003

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Arabidopsis Proteins
Arabidopsis
protein kinases
Protein Kinases
phosphotransferases (kinases)
Phosphotransferases
Growth
3-Phosphoinositide-Dependent Protein Kinases
TOR Serine-Threonine Kinases
70-kDa Ribosomal Protein S6 Kinases
Lipids
lipids
active sites
Catalytic Domain
phosphorylation
Phosphorylation
proteins

ASJC Scopus subject areas

  • Genetics

Cite this

Growth signalling pathways in Arabidopsis and the AGC protein kinases. / Bögre, László; Ökrész, L.; Henriques, Rossana; Anthony, Richard G.

In: Trends in Plant Science, Vol. 8, No. 9, 01.09.2003, p. 424-431.

Research output: Contribution to journalArticle

Bögre, László ; Ökrész, L. ; Henriques, Rossana ; Anthony, Richard G. / Growth signalling pathways in Arabidopsis and the AGC protein kinases. In: Trends in Plant Science. 2003 ; Vol. 8, No. 9. pp. 424-431.
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