The etiology of granulomatous hepatitis is extremely extensive for which the granulomatous reaction induced hepatic inflammation is characteristic. in the majority of cases it is part of a systemic disease but sometimes there is primer hepatic laesion in the background. The 21 year-old Caucasian female patient was taken to hospital having flu-like symptoms and icterus. While searching for the cause of her cholestatic hepatocellular laesion infections, tumors, storage diseases were excluded. However the root cause could not be identified. The histology showed granulomatous reaction, inflammation, intrahepatic bile duct proliferation and micronodular cirrhosis in the liver tissue. Taken it into consideration together with the clinical picture and the laboratory findings primer sclerotising cholangitis was rendered probable. Her state deteriorated and even the necessity of liver transplantation emerged. The patient was treated with ursodeoxycholic acid which resulted in a remission lasting for years now. Two years after the onset of the hepatic disease pancolitis ulcerosa with the affection of the ileum terminalis was found by the patient which supports the diagnosis of primary sclerotising cholangitis.
|Translated title of the contribution||Granulomatous hepatitis successfully treated with ursodeoxycholic acid|
|Number of pages||6|
|Publication status||Published - Aug 6 2006|
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