Granular cell variant of atypical fibroxanthoma

Zsolt Orosz, János Kelemen, Z. Szentirmay

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

We report a case of atypical fibroxanthoma of the ear in which the dominant part of the tumor has granular cell appearance. Areas identical to conventional atypical fibroxanthoma were present only at the lateral infiltrating borders. Histologically the granular cells resembled those of the classical granular cell tumors but exhibited significant pleomorphism and a high mitotic rate. Immunostains for vimentin, CD68 and NK1/C3 were positive but for S-100, HMB-45, myogenic and epithelial markers were negative. The predominance of the granular cells in an atypical fibroxanthoma supports the concept that a small subset of tumors with granular cell phenotype are of nonneural origin.

Original languageEnglish
Pages (from-to)244-247
Number of pages4
JournalPathology and Oncology Research
Volume2
Issue number4
DOIs
Publication statusPublished - Dec 1996

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Granular Cell Tumor
Vimentin
Ear
Phenotype

Keywords

  • atypical fibroxanthoma
  • fihrohistiocytie tumors
  • granular cells

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Oncology
  • Cancer Research

Cite this

Granular cell variant of atypical fibroxanthoma. / Orosz, Zsolt; Kelemen, János; Szentirmay, Z.

In: Pathology and Oncology Research, Vol. 2, No. 4, 12.1996, p. 244-247.

Research output: Contribution to journalArticle

Orosz, Zsolt ; Kelemen, János ; Szentirmay, Z. / Granular cell variant of atypical fibroxanthoma. In: Pathology and Oncology Research. 1996 ; Vol. 2, No. 4. pp. 244-247.
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