Gradient- and Sensitivity-Enhanced TOCSY Experiments

K. Kövér, Dušan Uhrín, Victor J. Hruby

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

A pulsed field gradient version of the sensitivity-enhanced 2D TOCSY experiment is proposed which yields high-quality spectra with improved sensitivity and a minimum of two scans per t1 increment. For rapid acquisition of ID TOCSY spectra, the 1D DPFGSE-TOCSY experiment was modified to include phase-encoded multiple-selective excitation followed by a simple spectral editing. Combination of these two building blocks is used in a sensitivity-enhanced 2D analog of the 3D TOCSY-TOCSY experiment which provides an efficient tool for resolving severely overlapped signals of oligomers in short experimental time.

Original languageEnglish
Pages (from-to)162-168
Number of pages7
JournalJournal of Magnetic Resonance
Volume130
Issue number2
Publication statusPublished - Feb 1998

Fingerprint

gradients
sensitivity
editing
Experiments
oligomers
Oligomers
acquisition
analogs
excitation

Keywords

  • 1D DPFGSE-TOCSY
  • 2D analog of 3D TOCSY-TOCSY
  • Echo-antiecho selection
  • Gradient version of 2D TOCSY
  • Multiple-selective excitation
  • Sensitivity enhancement

ASJC Scopus subject areas

  • Molecular Biology
  • Physical and Theoretical Chemistry
  • Spectroscopy
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics

Cite this

Gradient- and Sensitivity-Enhanced TOCSY Experiments. / Kövér, K.; Uhrín, Dušan; Hruby, Victor J.

In: Journal of Magnetic Resonance, Vol. 130, No. 2, 02.1998, p. 162-168.

Research output: Contribution to journalArticle

Kövér, K, Uhrín, D & Hruby, VJ 1998, 'Gradient- and Sensitivity-Enhanced TOCSY Experiments', Journal of Magnetic Resonance, vol. 130, no. 2, pp. 162-168.
Kövér, K. ; Uhrín, Dušan ; Hruby, Victor J. / Gradient- and Sensitivity-Enhanced TOCSY Experiments. In: Journal of Magnetic Resonance. 1998 ; Vol. 130, No. 2. pp. 162-168.
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