Gold-Catalyzed Direct Alkynylation of Azulenes

A. Székely, Áron Péter, Klára Aradi, Gergely L. Tolnai, Z. Novák

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A novel catalytic method for the direct C-H alkynylation of azulenes is developed. The gold catalyzed functionalization of this special carbacycle is achieved with hypervalent iodonium reagent TIPS-EBX under mild reaction conditions. With the aid of the developed procedure, several TIPS alkynylated azulene derivatives were synthesized bearing important functional groups for further functionalization.

Original languageEnglish
Pages (from-to)954-957
Number of pages4
JournalOrganic Letters
Volume19
Issue number4
DOIs
Publication statusPublished - Feb 17 2017

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Azulenes
Bearings (structural)
azulene
Gold
Functional groups
reagents
gold
Derivatives

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Gold-Catalyzed Direct Alkynylation of Azulenes. / Székely, A.; Péter, Áron; Aradi, Klára; Tolnai, Gergely L.; Novák, Z.

In: Organic Letters, Vol. 19, No. 4, 17.02.2017, p. 954-957.

Research output: Contribution to journalArticle

Székely, A. ; Péter, Áron ; Aradi, Klára ; Tolnai, Gergely L. ; Novák, Z. / Gold-Catalyzed Direct Alkynylation of Azulenes. In: Organic Letters. 2017 ; Vol. 19, No. 4. pp. 954-957.
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