Glycogen-enzymes containing bodies in type 2 fibres of tenotomized muscles in the rat.

L. Józsa, M. Kvist, M. Lehto, A. Réffy, T. Vieno

Research output: Contribution to journalArticle

Abstract

Inclusion bodies containing glycogen-enzymes were found in 30 to 60% of type 2 fibres of tenotomized calf muscles (m. gastrocnemius, m. soleus, m. plantaris) in rats, using histochemical reactions. The bodies appeared within 1 week after the tenotomy and were localized both in the central and the subsarcolemmal regions and rarely extruded into the extracellular space. These aggregates are 3 to 15 microns in length and 2 to 11 microns in diameter. In addition to glycogen, these bodies also contained various enzymes of the glycogen metabolism such as phosphorylase, a branching enzyme, and glucose-6-phosphatase, but showed no NADH-reductase, lactate dehydrogenase, or myofibrillar ATP-ase activity. The results indicate that glycogen-enzymes containing bodies are a degenerative phenomenon, which occurs only in type 2 fibres of the tenotomized muscles.

Original languageEnglish
Pages (from-to)519-528
Number of pages10
JournalGegenbaurs morphologisches Jahrbuch
Volume135
Issue number3
Publication statusPublished - 1989

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Somatotypes
Glycogen
Muscles
Enzymes
1,4-alpha-Glucan Branching Enzyme
Fast-Twitch Muscle Fibers
Tenotomy
Glucose-6-Phosphatase
Phosphorylases
Inclusion Bodies
Extracellular Space
L-Lactate Dehydrogenase
NAD
Oxidoreductases
Adenosine Triphosphate

ASJC Scopus subject areas

  • Medicine(all)

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Glycogen-enzymes containing bodies in type 2 fibres of tenotomized muscles in the rat. / Józsa, L.; Kvist, M.; Lehto, M.; Réffy, A.; Vieno, T.

In: Gegenbaurs morphologisches Jahrbuch, Vol. 135, No. 3, 1989, p. 519-528.

Research output: Contribution to journalArticle

Józsa, L. ; Kvist, M. ; Lehto, M. ; Réffy, A. ; Vieno, T. / Glycogen-enzymes containing bodies in type 2 fibres of tenotomized muscles in the rat. In: Gegenbaurs morphologisches Jahrbuch. 1989 ; Vol. 135, No. 3. pp. 519-528.
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