Glycan microarrays: New angles and new strategies

Boglarka Donczo, Janos Kerekgyarto, Zoltan Szurmai, Andras Guttman

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

Carbohydrate microarrays, comprising hundreds to thousands of different glycan structures on solid surfaces in a spatially discrete pattern, are sensitive and versatile tools for the analysis of glycosylation changes in complex biological samples. Glycoarrays are also suitable for monitoring multiple molecular interactions with biomolecules where sugars are involved, offering a large variety of bioassay options. In this paper we review the most important glycan microarray types currently used with their main applications, and discuss some of the future challenges the technology faces.

Original languageEnglish
Pages (from-to)2650-2657
Number of pages8
JournalAnalyst
Volume139
Issue number11
DOIs
Publication statusPublished - May 6 2014

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ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy
  • Electrochemistry

Cite this

Donczo, B., Kerekgyarto, J., Szurmai, Z., & Guttman, A. (2014). Glycan microarrays: New angles and new strategies. Analyst, 139(11), 2650-2657. https://doi.org/10.1039/c3an02289g