Genomic approach to complex diseases

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The complex or multifactorial diseases are those which develop through interactions of often hundreds of genes and environmental factors. The complex diseases like cancer, asthma, hypertension, diabetes mellitus, cardiovascular diseases or Alzheimer disease are often very frequent, it can even be said that more or less everybody is affected by some of them. In this review it is discussed why it is important to study the genomic background of the complex diseases and the main genomic methods are summarized. Next, the difficulties of these studies are shown and discussed what the reason of the missing heritability of the complex diseases can be. In the end some developments are shown which try to cope with these problems.

Original languageEnglish
Title of host publicationIFMBE Proceedings
PublisherSpringer Verlag
Pages1-6
Number of pages6
Volume50
ISBN (Print)9789812875723
DOIs
Publication statusPublished - 2015
Event1st European Biomedical Engineering Conference for Young Investigators, ENCY2015 - Budapest, Hungary
Duration: May 28 2015May 30 2015

Other

Other1st European Biomedical Engineering Conference for Young Investigators, ENCY2015
CountryHungary
CityBudapest
Period5/28/155/30/15

Fingerprint

Medical problems
Genes

Keywords

  • Genetic markers
  • Genetic variants
  • Genomic methods
  • Missing heritability
  • Multifactorial diseases

ASJC Scopus subject areas

  • Biomedical Engineering
  • Bioengineering

Cite this

Szalai, C. (2015). Genomic approach to complex diseases. In IFMBE Proceedings (Vol. 50, pp. 1-6). Springer Verlag. https://doi.org/10.1007/978-981-287-573-0_1

Genomic approach to complex diseases. / Szalai, C.

IFMBE Proceedings. Vol. 50 Springer Verlag, 2015. p. 1-6.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Szalai, C 2015, Genomic approach to complex diseases. in IFMBE Proceedings. vol. 50, Springer Verlag, pp. 1-6, 1st European Biomedical Engineering Conference for Young Investigators, ENCY2015, Budapest, Hungary, 5/28/15. https://doi.org/10.1007/978-981-287-573-0_1
Szalai C. Genomic approach to complex diseases. In IFMBE Proceedings. Vol. 50. Springer Verlag. 2015. p. 1-6 https://doi.org/10.1007/978-981-287-573-0_1
Szalai, C. / Genomic approach to complex diseases. IFMBE Proceedings. Vol. 50 Springer Verlag, 2015. pp. 1-6
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