Genetic heterogeneity and recombination in human type 2 astroviruses

S. De Grazia, M. C. Medici, P. Pinto, P. Moschidou, F. Tummolo, A. Calderaro, F. Bonura, K. Banyai, G. M. Giammanco, V. Martella

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Abstract

Novel lineages of human astrovirus (HAstV) types 2, 2c, and 2d have been identified. Upon sequencing of the 3′ end of the genome, the type 2c and 2d HAstVs were found to be open reading frame 1b (ORF1b)-ORF2 recombinant, with ORF1b being derived from type 3 and type 1 HAstVs, respectively. An ORF2 interlineage recombinant strain, 2c/2b, was also identified.

Original languageEnglish
Pages (from-to)3760-3764
Number of pages5
JournalJournal of Clinical Microbiology
Volume50
Issue number11
DOIs
Publication statusPublished - Nov 1 2012

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ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

De Grazia, S., Medici, M. C., Pinto, P., Moschidou, P., Tummolo, F., Calderaro, A., Bonura, F., Banyai, K., Giammanco, G. M., & Martella, V. (2012). Genetic heterogeneity and recombination in human type 2 astroviruses. Journal of Clinical Microbiology, 50(11), 3760-3764. https://doi.org/10.1128/JCM.02102-12