Genetic heterogeneity and recombination in canine noroviruses

Vito Martella, Nicola Decaro, Eleonora Lorusso, Arianna Radogna, Paschalina Moschidou, Francesca Amorisco, Maria Stella Lucente, Costantina Desario, Viviana Mari, Gabriella Elia, Krisztian Banyai, Leland Eugene Carmichael, Canio Buonavoglia

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

Alphatronlike (genogroup IV [GIV]) noroviruses (NoVs) have been recently identified in carnivores. By screening a collection of 183 fecal samples collected during 2007 from dogs with enteric signs, the overall NoV prevalence was found to be 2.2% (4/183). A unique strain, Bari/91/07/ITA, resembled GIV.2 NoVs in its ORF1 (polymerase complex), while it was genetically unrelated in its full-length ORF2 (capsid gene) to GIV animal and human NoVs (54.0 to 54.4% amino acid identity) and to any other NoV genogroup (<54.7% amino acid identity). It displayed the highest identity (58.1% amino acid identity) to unclassified human strain Chiba/040502/04/Jp. Interestingly, the very 5′ end of ORF2 of the canine virus matched short noroviral sequences (88.9% nucleotide identity and 98.9% amino acid identity) identified from oysters in Japan, indicating that similar viruses may be common environmental contaminants.

Original languageEnglish
Pages (from-to)11391-11396
Number of pages6
JournalJournal of Virology
Volume83
Issue number21
DOIs
Publication statusPublished - Nov 1 2009

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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    Martella, V., Decaro, N., Lorusso, E., Radogna, A., Moschidou, P., Amorisco, F., Lucente, M. S., Desario, C., Mari, V., Elia, G., Banyai, K., Carmichael, L. E., & Buonavoglia, C. (2009). Genetic heterogeneity and recombination in canine noroviruses. Journal of Virology, 83(21), 11391-11396. https://doi.org/10.1128/JVI.01385-09