Genetic diversity and population structure of the synthetic pannon white rabbit revealed by pedigree analyses

I. Nagy, I. Curik, I. Radnai, I. Cervantes, P. Gyovai, R. Baumung, J. Farkas, Z. Szendro

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Demographic history, current status, and efficiency of the mating strategy were analyzed us-ing the pedigree of Pannon White (PW) rabbits born between 1992 and 2007. Potential accumulation of det-rimental effects and loss of genetic diversity were also considered. Calculations and estimates were done most often for rabbits born in 2007, whereas other reference populations (REFPOPXXXX) were specified explicitly. The pedigree contained 4,749 individuals and 580 found-ers, and its completeness was 82.1% up to 10 and 94.5% up to 5 generations, respectively. Generation intervals through different pathways averaged 1.2 yr. When ad-justed to the pedigree completeness, the amount of in-breeding (Fi) of rabbits was comparable (5.54%) with that of other livestock populations, whereas the 10 (30) founders contributing the most to inbreeding explained a large part of the population inbreeding [i.e., 42.24% (73.18%)]. The ancestral inbreeding coefficient of REF-POP2004 (10.67%) was one-half that of REFPOP2007 (20.66%), showing its strong dependence on pedigree length. Family variance, inbreeding, and realized ef-fective population size were 84.18 (REFPOP2006; this variable could not be calculated for the last year ex-amined), 37.19, and 91.08, respectively. The effective numbers of ancestors, founders, and founder genomes were 48, 26, and 7.33, respectively. Although the cir-cular mating scheme applied was generally effective, the large accumulated reduction in genetic variability indicates the need to revise and improve the current breeding strategy.

Original languageEnglish
Pages (from-to)1267-1275
Number of pages9
JournalJournal of Animal Science
Volume88
Issue number4
DOIs
Publication statusPublished - Apr 1 2010

Keywords

  • Genetic diversity
  • Inbreeding coefficient
  • Pannon white rabbit
  • Pedigree analysis

ASJC Scopus subject areas

  • Food Science
  • Animal Science and Zoology
  • Genetics

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