Genetic characterization of a novel picornavirus in Algerian bats: co-evolution analysis of bat-related picornaviruses

Safia Zeghbib, Róbert Herczeg, Gábor Kemenesi, Brigitta Zana, Kornélia Kurucz, Péter Urbán, Mónika Madai, Fanni Földes, Henrietta Papp, Balázs Somogyi, Ferenc Jakab

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Abstract

Bats are reservoirs of numerous zoonotic viruses. The Picornaviridae family comprises important pathogens which may infect both humans and animals. In this study, a bat-related picornavirus was detected from Algerian Minioptreus schreibersii bats for the first time in the country. Molecular analyses revealed the new virus originates to the Mischivirus genus. In the operational use of the acquired sequence and all available data regarding bat picornaviruses, we performed a co-evolutionary analysis of mischiviruses and their hosts, to authentically reveal evolutionary patterns within this genus. Based on this analysis, we enlarged the dataset, and examined the co-evolutionary history of all bat-related picornaviruses including their hosts, to effectively compile all possible species jumping events during their evolution. Furthermore, we explored the phylogeny association with geographical location, host-genus and host-species in both data sets.

Original languageEnglish
Article number15706
JournalScientific reports
Volume9
Issue number1
DOIs
Publication statusPublished - Dec 1 2019

ASJC Scopus subject areas

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    Zeghbib, S., Herczeg, R., Kemenesi, G., Zana, B., Kurucz, K., Urbán, P., Madai, M., Földes, F., Papp, H., Somogyi, B., & Jakab, F. (2019). Genetic characterization of a novel picornavirus in Algerian bats: co-evolution analysis of bat-related picornaviruses. Scientific reports, 9(1), [15706]. https://doi.org/10.1038/s41598-019-52209-2