Az irritabilis bél szindróma genetikai háttere

Translated title of the contribution: Genetic background of irritable bowel syndrome

Research output: Contribution to journalArticle

1 Citation (Scopus)


Irritable bowel syndrome (IBS) is a functional disorder which affects the 20% of the population. The exact origin is unknown. IBS is the result of interaction of genes and environmental factors. Familial aggregation and higher concordance rate of monozygotic twins compared to dizygotic twins provide evidence for the importance of genetic factors in the pathogenesis of IBS. Interest has focused on genetic variants of serotonin transporter and receptors, because of their role in gut motility, visceral sensitivity, immun processes and mood. Firm conclusions about the role of serotonin system, as well as other neuroreceptors, G-proteins, cytokine polymorphisms in the pathogenesis of IBS cannot be made.

Translated title of the contributionGenetic background of irritable bowel syndrome
Original languageHungarian
Pages (from-to)1167-1170
Number of pages4
JournalOrvosi hetilap
Issue number25
Publication statusPublished - Jun 25 2006

ASJC Scopus subject areas

  • Medicine(all)

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