Genetic analysis of chorion formation in Drosophila melanogaster

I. The effects of one somatic-specific and seven germ-line-specific mutations.

V. K. Galanopoulos, W. Orr, J. Szabad, F. C. Kafatos

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Eight X-linked recessive female sterile mutations, derived from a hybrid dysgenic screen of Drosophila melanogaster and representing eight distinct loci, have been characterized by genetic and ultrastructural analysis. Four have abnormal respiratory appendages, three have essentially normal appendages but show moderate defects in the endochorion, and one mutant, fs(1)ne1a, exhibits major defects in both the endochorion and the respiratory appendages. Germ line clones of all eight mutants were generated using the dominant female sterile technique. Seven of the eight mutations are germ line specific, indicating that, although the eggshell is produced by the follicular cells, germ line functions play a significant role in its elaboration. The mutant that shows major defects, fs(1)ne1a, is somatic line specific, and exerts its effect in the ovary.

Original languageEnglish
Pages (from-to)87-97
Number of pages11
JournalDevelopmental Genetics
Volume10
Issue number2
Publication statusPublished - 1989

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Chorion
Germ-Line Mutation
Drosophila melanogaster
Germ Cells
Egg Shell
Ovary
Clone Cells
Mutation

ASJC Scopus subject areas

  • Cell Biology
  • Developmental Biology
  • Genetics

Cite this

Genetic analysis of chorion formation in Drosophila melanogaster : I. The effects of one somatic-specific and seven germ-line-specific mutations. / Galanopoulos, V. K.; Orr, W.; Szabad, J.; Kafatos, F. C.

In: Developmental Genetics, Vol. 10, No. 2, 1989, p. 87-97.

Research output: Contribution to journalArticle

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